SYNTHESIS AND ANTI-MICROBIAL ACTIVITY OF N'-(2-HYDROXY-5-NITROBENZYLIDENE) ISONICOTINOHYDRAZIDE
نویسندگان
چکیده
منابع مشابه
N′-(2-Chloro-5-nitrobenzylidene)isonicotinohydrazide
The title compound, C(13)H(9)ClN(4)O(3), was synthesized by the condensation reaction of 2-chloro-5-nitro-benzaldehyde with isonicotinohydrazide in a methanol solution. The mol-ecule of the compound displays a trans configuration with respect to the C=N and C-N bonds. The dihedral angle between the benzene and pyridine rings is 12.1 (2)°. In the crystal structure, adjacent mol-ecules are linked...
متن کامل(E)-N′-(5-Bromo-2-methoxybenzylidene)isonicotinohydrazide
The asymmetric unit of the title compound, C(14)H(12)BrN(3)O(2), contains two independent mol-ecules in which the dihedral angles between the benzene ring and the pyridine ring are 24.4 (6) and 23.7 (6)°. The mol-ecules exist in a trans configuration with respect to the central methyl-idene units. In the crystal, mol-ecules are linked through inter-molecular N-H⋯O hydrogen bonds, forming chains...
متن کاملCrystal structures of (E)-N′-(2-hydroxy-5-methylbenzylidene)isonicotinohydrazide and (E)-N′-(5-fluoro-2-hydroxybenzylidene)isonicotinohydrazide
Two derivatives of the well-known iron chelator, (E)-N'-(2-hy-droxy-benzyl-idene)isonicotinohydrazide (SIH), substituted in the 5-position of the 2-hy-droxy-benzene ring by a methyl and a fluorine group viz. (E)-N'-(2-hy-droxy-5-methyl-benzyl-idene)isonicotinohydrazide, C14H13N3O2, (I), and (E)-N'-(5-fluoro-2-hy-droxy-benzyl-idene)isonicotinohydrazide, C13H10FN3O2, (II), have been prepared and ...
متن کاملN′-[(5-Methylfuran-2-yl)methylene]isonicotinohydrazide
The title compound, C(12)H(11)N(3)O(2), was prepared by the reaction of isonicotinohydrazide and 5-methyl-furan-2-carbalde-hyde. The pyridine ring makes a dihedral angle of 46.90 (9)° with the mean plane of the furan ring. The crystal packing is stabilized by a bifurcated inter-molecular N-H⋯(N,O) inter-action.
متن کاملSynthesis and in vitro Anti-Bacterial Activity of 2-(5-Nitro-2-heteroaryl)-1,3,4-Thiadiazole Derivatives
A new series of 2-(5-nitro-2-heteroaryl)-1,3,4-thiadiazole derivatives, including nitro furan, nitro thiophene and nitro imidazole, were synthesized and screened in vitro for their inhibitory activity against eight bacterial strains. The results showed that most of the synthesized compounds were active against Gram-positive bacteria, determined by MIC method. Among them, compounds <str...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: SERIES CHEMISTRY AND TECHNOLOGY
سال: 2019
ISSN: 2224-5286,2518-1491
DOI: 10.32014/2019.2518-1491.14